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> I think the data was clear enough that the vaccines are worth getting. However, this seems to shatter any thoughts folks may have that they are safer to other

> I think the data was clear enough that the vaccines are worth getting. However, this seems to shatter any thoughts folks may have that they are safer to others when they are vaccinated? That's not the correct conclusion from this statement though. Taking the vaccine increases the likelihood that your immune system will be able to get kill the virus almost immediately after exposure, so that you don't start exhibiting symptoms at all. You can still get COVID and thus exhibit symptoms after being vaccinated, it's just less likely. However, this statement is concerning those who got infected and then started exhibiting symptoms. Of those, i.e. when your immune system wasn't able to immediately deal with the virus and needs to learn how to do it, the viral load expelled was roughly the same in every case, peaking at 8 days. That's probably not too unexpected really, but it does seem to indicate that the immunity given by the vaccine is probably all or nothing for any particular variant you're exposed to - it either works immediately and stops you getting ill, or the immune system still has to start from scratch in figuring it out.

taeric 3y ago
I'm game to see more on that. This study specifically, shows that you can be vaccinated and get it. You will have fewer symptoms, but still shed just as much virus. That is literally what their callout was about, no? If you are claiming that you are less likely to get it when you are vaccinated, that kind of contradicts a lot of what I've seen out there. I'm happy to learn that is mostly paranoia, though? I haven't actually followed too much there, as it doesn't seem to impact my behavior. I'll get vaccinated when eligible, just as I have done for other things for most of my life.
- weaksauce 3y ago
  > This study specifically, shows that you can be vaccinated and get it. You will have fewer symptoms, but still shed just as much virus. no. the study shows that the vaccine status doesn't change how much you shed for a given level of symptoms. aka high symptomatic => high viral shed. lowly symptomatic => low viral shed. from the actual pre-print's[0] abstract: > We further found that levels of exhaled viral RNA increased with self-rated symptom-severity, though individual variation was high. Levels of exhaled viral RNA did not differ across age, sex, time of day, vaccination status or viral variant. 0. https://www.medrxiv.org/content/10.1101/2023.09.06.23295138v1 https://www.medrxiv.org/content/10.1101/2023.09.06.23295138v...
  - taeric 3y ago
    Apologies, that is inline with what I meant. You will shed proportional to your level of symptoms. If you were vaccinated and still get heavily sick, you will still shed as any other heavily sick person. That said, the caveat of "though individual variation was high" makes me curious if some of the correlation to self-rated symptom goes away when you only look at something like vaccination status.

taeric 3y ago

I'm game to see more on that. This study specifically, shows that you can be vaccinated and get it. You will have fewer symptoms, but still shed just as much virus. That is literally what their callout was about, no? If you are claiming that you are less likely to get it when you are vaccinated, that kind of contradicts a lot of what I've seen out there. I'm happy to learn that is mostly paranoia, though? I haven't actually followed too much there, as it doesn't seem to impact my behavior. I'll get vaccinated when eligible, just as I have done for other things for most of my life.

weaksauce 3y ago
> This study specifically, shows that you can be vaccinated and get it. You will have fewer symptoms, but still shed just as much virus. no. the study shows that the vaccine status doesn't change how much you shed for a given level of symptoms. aka high symptomatic => high viral shed. lowly symptomatic => low viral shed. from the actual pre-print's[0] abstract: > We further found that levels of exhaled viral RNA increased with self-rated symptom-severity, though individual variation was high. Levels of exhaled viral RNA did not differ across age, sex, time of day, vaccination status or viral variant. 0. https://www.medrxiv.org/content/10.1101/2023.09.06.23295138v1 https://www.medrxiv.org/content/10.1101/2023.09.06.23295138v...
- taeric 3y ago
  Apologies, that is inline with what I meant. You will shed proportional to your level of symptoms. If you were vaccinated and still get heavily sick, you will still shed as any other heavily sick person. That said, the caveat of "though individual variation was high" makes me curious if some of the correlation to self-rated symptom goes away when you only look at something like vaccination status.