Just put e. coli in an ultracentrifuge and do a few hundred generations of serial passaging and see what evolves, for starters. You could do this pretty cheaply

Just put e. coli in an ultracentrifuge and do a few hundred generations of serial passaging and see what evolves, for starters. You could do this pretty cheaply without waiting decades or killing mammals. Apparently e. coli can proliferate happily at almost half a million g... https://phys.org/news/2011-04-bacteria-extreme-gravity.html#:~:text=With%20the%20use%20of%20a,growth%20rate%20was%20not%20affected https://phys.org/news/2011-04-bacteria-extreme-gravity.html#....