3 ms·
Perturbation analysis of spatial single cell RNA-seq (2021)
- tetris11 3y agoThe aim is to see if stressed and non-stressed cells cluster separately using spatial transcriptomics? As always with this field, highly fascinating space for algorithmic experimentation, but since a lot of it is completely new territory (cell development is a mature but open field) half the time there is no real validation for the results that you get, other than going to a cell biologist and asking "do these trends this maybe possibly perhaps suggest X, and if not, (uses a different comparison or reclusters with different prior filter) how about now?"