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>Personally I prefer the effect of high doses of manganese (chloride) on insulin and the stimulating effect insulin has on the immune system. Could you go into

• darkclouds 3y ago
  No I'm saying manganese helps regulates insulin which in turn helps modulate parts of the immune system. [1] It helps to smooth the blood sugar spike. Chromium reduces insulin sensitivity which is helpful for cells especially muscle which in turn increases stamina. There are plenty of studies which call into question the RDA's for supplements and there are misleading studies like [3]. For example, [2] (Zinc) deficiency during pregnancy causes irreversible effects on the newborn such as growth impairment, spontaneous abortion, congenital malformations and poor birth outcomes. The same probably exists for other supplements and likewise over exposure will also introduce problems like nickel over exposure can cause fibrotic lung in animal experiments which could explain why some people are born with cystic fibrosis. In this example [3], the subjects are only consuming 200micrograms of chromium. I'm not surprised they didnt see any effect, the RDA is 400ug, but some body builders have been known to take upto 2.4g aka 2,400mg aka 2,400,000ug and have seen effects (cant find the study now), but the weight training muddies the water so to speak. And the chromium intake assumes there is enough manganese in the diet to help produce enough insulin and thus smooth the blood sugar levels in the first place. Zinc plays a role at stabilising cell membranes, it can help reduce the need for a vit E intake which also helps protect cell membranes and is also heavily concentrated in organs like the pancreas. And whilst non digestive exposure to metals like zinc and manganese can cause problems, the digestive system is very capable at removing excess intakes via the bile acids, helping to reduce any risks. Zinc, manganese and chromium will all have an effect on the immune system, but as manganese is most commonly associated with insulin production, I only mentioned the manganese. This study [4] shows that chromium alters the immune response by immunostimulatory or immunosuppressive processes, by altering the insulin resistance of cells. We are very complex chemical reactions, so trying to get the right intake seems to be a logical first step and with todays technology, and the complete absence of medical experts asking about diet in the first place, how can they even do their job properly for long term illnesses? So in this reprogramming of cancer cells, yes its a another scientific achievement but is this another achievement once the horse has bolted and should we actually be looking more at the quality and nutrition of our food and environment in order to avoid reactionary medicine? [1] https://www.medicalnewstoday.com/articles/322946#:~:text=%E2%80%9CThe%20link%20between%20insulin%20and,by%20metabolic%20signals%20from%20insulin.%E2%80%9D https://www.medicalnewstoday.com/articles/322946#:~:text=%E2... [2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262205/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262205/ [3] https://pubmed.ncbi.nlm.nih.gov/9861607/ https://pubmed.ncbi.nlm.nih.gov/9861607/ [4] https://academic.oup.com/femspd/article/34/1/1/498748 https://academic.oup.com/femspd/article/34/1/1/498748