What novel problem would you want startup founders to solve? Are those problems solvable with current technologies? Is there a distribution model that'll work f

What novel problem would you want startup founders to solve? Are those problems solvable with current technologies? Is there a distribution model that'll work for that solution? Will the unit economics work? How big is the market for this novel problem? Is it worth spending time and money on this problem instead of a "generic product" that seems to be making more money?