Incidentally mescaline tends to be one of the exceptions from the "legalize all plant medicine" crowd. Apparently it's a lot of effort to cultivate peyote; the

Incidentally mescaline tends to be one of the exceptions from the "legalize all plant medicine" crowd. Apparently it's a lot of effort to cultivate peyote; there isn't much of it, and it's associated with tribal practices. People advocating for legalization tend to leave out peyote because they don't want people competing with tribal shaman for access to it. I believe there's another source (S. Pedro cactus?) that doesn't have the tribal history, and is thus considered a reasonable alternative for legalization.