People disagree on the definition of harm, therefore there will be preferences for law. On a societal scale, if there is a 1:N chance a drug or experience will

People disagree on the definition of harm, therefore there will be preferences for law. On a societal scale, if there is a 1:N chance a drug or experience will nullify your health and you will require society to bear the burden if your existence, then people in society may decide to attempt to minimize such occurrences through law. If N is 6 as in Russian Roulette, society might control what you might accidentally put in your body. If N is 1,000,000 like in driving, we might regulate the requirements of who can do that to minimize the chance of harming others and drive N higher. If N is 10,000 (for certain drugs) in terms of the chance you might overdose and harm yourself sufficiently, society might say the benefit isn’t worth the risk and ‘control what you do with your body.’