3 ms·
There was certainly no reason to believe, even at the time, that these vaccines would be any more durable over the long term against a rapidly evolving coronavi
by cempaka 3y ago
There was certainly no reason to believe, even at the time, that these vaccines would be any more durable over the long term against a rapidly evolving coronavirus than all of the previous attempts to develop such a vaccine. Seems like a lot of people were just hoping that would be the case because of the shiny new tech involved and because they were aggressively sold on the idea the vaccines were the key to "ending the pandemic." Plenty of immunologists at the time predicted that SARS-CoV-2 immune escape would come quickly and that vaccine protection would wear off quickly.
- peter422 3y agoMany very smart virologists at the time noted that other coronaviruses in circulation didn't mutate that much (as compared to something like influenza), so it really was not known to what expect and at what speed the virus would or could mutate.