3 ms·

> nobody with congenital blindness has developed schizophrenia What’s the rationale for why this might happen?

• tremon 3y ago
  You could posit that a necessary trigger for developing schizophrenia is (over)stimulation of the visual cortex. If that can't happen in blind people (I don't know if all blindness is the same), they'd be naturally protected without even having to consider a genetic component. But to me, very low incidence rate for both seems like a sufficient rationale. Given that there's both viral and genetic causes for congenital blindness, it just doesn't make sense to imply the protection is genetic: even if true, there would still be cases of schizophrenia among the people that were blinded by a viral infection in-utero.