3 ms·
There's a wide variety of bacteria that inhabit the GI tract, with tremendous diversity around the world. The extinction idea is interesting, but I've not seen
by soudiere 3y ago
There's a wide variety of bacteria that inhabit the GI tract, with tremendous diversity around the world. The extinction idea is interesting, but I've not seen any evidence that demonstrates anything like it in the literature.
https://sci-hub.se/https://www.nature.com/articles/s41586-019-0965-1 https://sci-hub.se/https://www.nature.com/articles/s41586-01...
Bacteriophage & fecal transplants are nice options to have for treatment, but don't address the underlying cause that resulted in the GI dysfunction.
- nextos 3y agoI don't think you are right. There is actually quite a lot of literature demonstrating how species present in hunter-gatherers are not present in the guts of individuals from industrialized societies. See e.g. https://doi.org/10.1016/j.cell.2023.05.046 https://doi.org/10.1016/j.cell.2023.05.046. Still, even if this was not the case at population level, my point would still hold. At individual level, many species are bimodal. With the wrong nutrients, infections, etc. your microbiome might fall into a state where you have none of them, as they have been outcompeted, and reversing that is incredibly difficult.