3 ms·
> can the viral vector reach those? I think yes from the article? The whole point of this therapy is to eliminate latent HIV from dormant cells that tradition
by whimsicalism 3y ago
> can the viral vector reach those?
I think yes from the article? The whole point of this therapy is to eliminate latent HIV from dormant cells that traditional small molecule retroviral therapy can't access.
> CRISPR does the cutting only, and you rely on cell repair mechanisms to mend the parts together again
But in this case, all we need is the cutting right because we don't care if the HIV survives the interaction.
Agreed on the quote
- j16sdiz 3y ago> But in this case, all we need is the cutting right because we don't care if the HIV survives the interaction. In the "what could possibly go wrong" scenario, if it survive this drives the virus for mutantion.
- civilitty 3y agoThat’s always a concern with HIV regardless of the treatment. Most therapies include several mechanisms to reduce the probability of adaptation significantly.