3 ms·
All exercise excerbates ME/CFS? Only certain types? Cochrane systemic review, "exercise therapy for chronic fatigue syndrome", 8 studies, 1518 participants "I
by soudiere 3y ago
All exercise excerbates ME/CFS? Only certain types?
Cochrane systemic review, "exercise therapy for chronic fatigue syndrome", 8 studies, 1518 participants
"Investigators compared exercise therapy with 'passive' control in eight trials, which enrolled 971 participants. Seven studies consistently showed a reduction in fatigue following exercise therapy at end of treatment, even though the fatigue scales used different scoring systems ... Serious adverse reactions were rare in both groups (RR 0.99, 95% CI 0.14 to 6.97; one study, 319 participants; moderate‐quality evidence)"
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419524/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419524/
Fairly plausible, mitchondrial biogensis is an adaption to exercise, it may be impaired in ME/CFS patients, but not totally inhibited, and more mitochondria may lessen the severity of the pathogenesis of ME/CFS.