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Last Thursday the Dutch News reported about findings at Amsterdam UMC of an enzyme IDO-2 that keeps being produced in long covid patients' cells. And that an ex
by rapnie 3y ago
Last Thursday the Dutch News reported about findings at Amsterdam UMC of an enzyme IDO-2 that keeps being produced in long covid patients' cells. And that an experimental cancer medicine manufactured by Bayer and BMS can put a stop to this. It was brought as an 'important step' in long covid research (that nonetheless would take years to lead to any broadly available cure). Unfortunately the article didn't publish links to papers.
[0] In Dutch: https://nos.nl/artikel/2486149-experimenteel-kankermedicijn-in-beeld-als-antwoord-op-longcovidklachten https://nos.nl/artikel/2486149-experimenteel-kankermedicijn-...
- maxboone 3y agohttps://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00294-3/fulltext https://www.thelancet.com/journals/ebiom/article/PIIS2352-39...
- FollowingTheDao 3y agoIDO2 is stimulated during any infection but ongoing IDO2 expression could come from an iron deficiency. Iron is the cofactor for TPH1 and TPH2 which turns tryptophan into serotonin. If that is not working the tryptophan will be turned into kynurenine by IDO1 and IDO2. https://www.mdpi.com/ijms/ijms-22-11714/article_deploy/html/images/ijms-22-11714-g001.png https://www.mdpi.com/ijms/ijms-22-11714/article_deploy/html/... Iron deficiency has been a common feature of LC for a while: https://timesofindia.indiatimes.com/life-style/health-fitness/health-news/is-iron-deficiency-an-after-effect-of-covid-infection-experts-answer-shed-light-on-the-signs-sources-and-supplementation/articleshow/92818880.cms https://timesofindia.indiatimes.com/life-style/health-fitnes...