SSRIs are popular because they are effective and safer than older antidepressants. And what depression interventions are incompatible with SSRIs but other drugs

SSRIs are popular because they are effective and safer than older antidepressants. And what depression interventions are incompatible with SSRIs but other drugs not understood completely also? What should SSRIs be called if the SSRI part is how they work indirectly? What would you call them now? And SNRIs? And MAOIs?