3 ms·
Strictly speaking, psychosis is more strongly related to excess serotonin, 'the molecule of stress and inflammation'. Doctors sometimes recognize 'Serotonin Syn
by tcj_phx 3y ago
Strictly speaking, psychosis is more strongly related to excess serotonin, 'the molecule of stress and inflammation'. Doctors sometimes recognize 'Serotonin Syndrome' in their ER patients: "too much serotonin causes signs and symptoms that can range from mild (shivering and diarrhea) to severe (muscle rigidity, fever and seizures)." Usually the Serotonin Syndrome is caused by a combination of prescriptions, or street drugs.
https://www.mayoclinic.org/diseases-conditions/serotonin-syndrome/symptoms-causes/syc-20354758 https://www.mayoclinic.org/diseases-conditions/serotonin-syn...
All the effective anti-psychotics seem to have anti-serotonin properties, in addition to their anti-dopamine effects. For example: "there are also recent studies that 'stumbled upon' the 'shocking' evidence that anti-dopamine drugs commonly used for treating schizophrenia such as haloperidol are actually potent serotonin antagonists as well." - http://haidut.me/?p=1297 http://haidut.me/?p=1297
One of you quoted my essay Cargo Cult Psychiatry in a comment on Sunday, on a submission of Feynman's Cargo Cult Science. I responded, then thought to submit my link to the original at Mad In America again: https://news.ycombinator.com/item?id=37110874 https://news.ycombinator.com/item?id=37110874
This paragraph from that comment is essential for helping anyone diagnosed with the label of "schizophrenia":
"The good news from the mental health world is that Chris Palmer, M.D. published Brain Energy [0] last year. I haven't read more than excerpts from google books [1]. My understanding is Dr. Palmer was a conventional palliative psychiatrist, then he had a patient whose schizophrenia improved on a ketogenic diet. The patient was able to discontinue antipsychotics: Dr. Palmer's mind was blown. Then he discovered the 70+ years of research establishing that mental health conditions are metabolic problems that can be successfully treated with pro-metabolic therapies.
Perhaps the most bold and disruptive
aspect of Brain Energy is understanding
precisely how and why medications that
harm metabolism might reduce mental
health symptoms.
The long-term consequences are of great
concern and require the urgent attention
of the psychiatric community.
-Chris Palmer, MD - https://twitter.com/ChrisPalmerMD/status/1687850270602981376 https://twitter.com/ChrisPalmerMD/status/1687850270602981376 [...]
[0] https://brainenergy.com/ https://brainenergy.com/ / [1] https://books.google.com/books?id=FoxlEAAAQBAJ&pg=PT233&dq=B https://books.google.com/books?id=FoxlEAAAQBAJ&pg=PT233&dq=B "
- psychphysic 3y agopimavanserin case in point
- tcj_phx 3y agoThanks for the tip: Pimavanserin has a unique mechanism of action relative to other antipsychotics, behaving as a selective inverse agonist of the serotonin 5-HT2A receptor, with 40-fold selectivity for this site over the 5-HT2C receptor and no significant affinity or activity at the 5-HT2B receptor or dopamine receptors.[2] -https://en.wikipedia.org/wiki/Pimavanserin https://en.wikipedia.org/wiki/Pimavanserin