Yes, you can have the reactor offline, with control rods inserted for launch. Then when you reach the requisite altitude, withdraw the control rods and start up

Yes, you can have the reactor offline, with control rods inserted for launch. Then when you reach the requisite altitude, withdraw the control rods and start up the reactor. In the event of a launch accident and potential destruction of the reactor, the enriched uranium fuel would be a chemical hazard (uranium is a heavy metal like lead), but only a mild radiation hazard (since there are no high-gamma fission products, and the uranium has undergone heavy purification prior to fuel fabrication).