I don't know Blazor, and it's difficult to tell from the webpage. But I can tell you that most of my model (business logic) code is written in Clojure and comp

I don't know Blazor, and it's difficult to tell from the webpage. But I can tell you that most of my model (business logic) code is written in Clojure and compiles to both JVM and ClojureScript. In other words, I use the same code on the server and on the client. I also use EDN (meaning Clojure) as the serialization format between them, so I avoid serializing to something non-native. All this buys a lot of incremental improvement. ClojureScript gets compiled using Google Closure compiler in "advanced" compilation mode — for those who might not know, this is not a "minifier", it's a whole-program transformer which does renaming and dead code elimination. The result is highly optimized JavaScript. I guess that's why there isn't much excitement about WebAssembly in Clojure circles — the current state of affairs is really good enough. In my experience (complex SaaS app), DOM operations are a performance bottleneck, not ClojureScript.