2 ms·
> further research shows they haven't tested for it's presence in breastmilk yet. What? This claim is easily falsifiable. Section 8.2, Lactation: > Availabl
by loeg 3y ago
> further research shows they haven't tested for it's presence in breastmilk yet.
What? This claim is easily falsifiable. Section 8.2, Lactation:
> Available data from a clinical lactation study in 14 women indicate that zuranolone is present in low levels in human milk.
> A steady-state milk study was conducted in 14 healthy lactating women treated with daily oral administration of 30 mg of ZURZUVAE for 5 days. At steady state (Day 5), the calculated maximum relative infant dose for ZURZUVAE was < 1%. The daily infant dose was low (approximately 0.0013 mg/kg/day), reflecting a mean relative infant dose of 0.357% compared to the maternal dose. Concentrations of ZURZUVAE in breastmilk were below the level of
quantification limit (BQL) by 4-6 days after the last dose.