3 ms·

I appreciate the clarity in the title that this study was in mice. At the same time, as a celiac, the title is basically common sense and I don't need a study t

by yosito 3y ago

I appreciate the clarity in the title that this study was in mice. At the same time, as a celiac, the title is basically common sense and I don't need a study to tell me that this applies to humans. One microscopic bread crumb and I'll have brain fog for a week.

dehrmann 3y ago
> the title is basically common sense and I don't need a study to tell me that this applies to humans Not sure how this is common sense. If it were mice engineered to have celiac disease or recently diagnosed humans, it might make sense. Extrapolating it to the general population of a different species in a part of the body not related to digestion is a bit of a leap.
- yosito 3y ago
  What I mean to say is that it is common sense to a celiac that gluten causes inflammation throughout the body and brain even of non-celiacs. I'm not extrapolating from the study, just saying that the study is concluding something that was already pretty obvious to many people.
  - swsieber 3y ago
    > [I]t is common sense to a _celiac_ that gluten causes inflammation throughout the body and brain even of _non-celiacs_ (emphasis mine) I don't follow how this is common sense. It looks like extrapolating from your condition (celiac) and projecting it onto those that don't have your condition (non-celiacs).
  - lame-robot-hoax 3y ago
    How is that common sense?
Zak 3y ago
> One microscopic bread crumb and I'll have brain fog for a week. It's widely known that a bread crumb will have harmful effects if you have celiac disease. A human who has a peanut allergy will have very negative effects from eating a fraction of a peanut. It's also widely known that foods that are fine for one species can have toxic effects in others. A well-known example is that chocolate is fine for humans (in moderation) but deadly to dogs in similar quantities. A finding that humans without an allergy or hypersensitivity to it react to wheat gluten with brain inflammation would be big news, as would a finding that a large fraction of the human population has a hypersensitivity.

by yosito 3y ago

dehrmann 3y ago

> the title is basically common sense and I don't need a study to tell me that this applies to humans Not sure how this is common sense. If it were mice engineered to have celiac disease or recently diagnosed humans, it might make sense. Extrapolating it to the general population of a different species in a part of the body not related to digestion is a bit of a leap.

yosito 3y ago
What I mean to say is that it is common sense to a celiac that gluten causes inflammation throughout the body and brain even of non-celiacs. I'm not extrapolating from the study, just saying that the study is concluding something that was already pretty obvious to many people.
- swsieber 3y ago
  > [I]t is common sense to a _celiac_ that gluten causes inflammation throughout the body and brain even of _non-celiacs_ (emphasis mine) I don't follow how this is common sense. It looks like extrapolating from your condition (celiac) and projecting it onto those that don't have your condition (non-celiacs).
- lame-robot-hoax 3y ago
  How is that common sense?

Zak 3y ago

> One microscopic bread crumb and I'll have brain fog for a week. It's widely known that a bread crumb will have harmful effects if you have celiac disease. A human who has a peanut allergy will have very negative effects from eating a fraction of a peanut. It's also widely known that foods that are fine for one species can have toxic effects in others. A well-known example is that chocolate is fine for humans (in moderation) but deadly to dogs in similar quantities. A finding that humans without an allergy or hypersensitivity to it react to wheat gluten with brain inflammation would be big news, as would a finding that a large fraction of the human population has a hypersensitivity.