3 ms·

“positive allosteric modulator of the GABAA receptor”, isn’t that a benzodiazepine? edit: nevermind i guess drugs are classified by their chemistry rather than

• trehalose 3y ago
  Drugs can be variously classified by their chemistry and/or by their effects. It's worth noting that GABA-A receptors have multiple allosteric sites, and different chemical classes of PAMs (positive allosteric modulators) may have differences in effects. (There certainly seems to be substantial overlap in effects, of course.)
• psychphysic 3y ago
  Technically it's a Z-drug (like Zolpidem/Ambien) which are non-benzodiazapine positive allosteric modulators of GABA_A However, since it's a neurosteroid most will probably not think of it as such. (It's name does begin with Z though... And end in -one like a steroid). Anyways, it's licensed for 2 weeks only, side effects are drowsiness, sleepiness and cognitive impairment. You mustn't drive within 12 hours of a dose. It's best effects are where the depression is associated with insomnia and anxiety. It was compared to placebo not Alprazolam (Xanax) which has some antidepressant activity.