Manually adjusting timings is somewhat obsolete since the introduction of XMP, but you can still set all the subtimings on modern boards, most people just don't

Manually adjusting timings is somewhat obsolete since the introduction of XMP, but you can still set all the subtimings on modern boards, most people just don't bother (although the gains can be not insignificant, especially if the XMP profile is poor). It's still dozens of parameters.