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What do you suspect will be the practical uses of this? Could it help researchers run experiments to develop better fertility protocols? Or depending on costs,

What do you suspect will be the practical uses of this? Could it help researchers run experiments to develop better fertility protocols? Or depending on costs, fertility clinics could test various protocols to find the optimal "hormone environment" for promoting high quality egg development? Or is this going to a more "out there" direction as in you could grow an egg entirely in vitro for later fertilization and implantation?

Metacelsus 3y ago
1 and 2: Yes that's what we're doing (in partnership with Gameto, the startup commercializing this tech). See our recent preprints: https://www.biorxiv.org/content/10.1101/2023.03.27.534477v2 https://www.biorxiv.org/content/10.1101/2023.03.27.534477v2 and https://www.biorxiv.org/content/10.1101/2023.03.27.534479v2 https://www.biorxiv.org/content/10.1101/2023.03.27.534479v2 3: I'm definitely excited about in vitro oogenesis and that's the direction I want to take this in the future. Right now, we're not able to reliably get the germ cells to do meiosis, so that's what I'm working on.
- Teever 3y ago
  How long until we're looking at a home appliance that can grow a baby to maturation from a genetic sample? What are the biggest bottlenecks? How do you anticipate such a device will be regulated? What do you anticipate will be the response from the pro-life right? From the antiscience antivax type community?
  - Metacelsus 3y ago
    That's a completely different technology, artificial wombs are much harder than artificial ovaries. Very unlikely within 20 years, I won't speculate past that point.
    - deleted 3y ago
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