The animal analogue of Alzheimer's has been very, very thoroughly demonstrated to be an entire failure for predicting the effect of interventions. Still, studyi

The animal analogue of Alzheimer's has been very, very thoroughly demonstrated to be an entire failure for predicting the effect of interventions. Still, studying that failed analogue (to the wholesale exclusion of attention to the actual disease in humans) has been a good career path for an entire generation of biochemists. One wonders what they could pivot to when it is finally abandoned; and what would need to happen before that could be achieved. As it is, those biochemists directly control $2B in grants to themselves, and show little appetite for change.