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You know, most of that stuff you hear about are bad takes on science. Science has moved into the realm of trying to understand complex systems with a lot of noi

• jacquesm 3y ago
  Exactly, it's like sifting a mountain of ore looking for diamonds. The original Korean team has essentially been doing a slightly guided brute force search in a domain that they thought was promising doing 100's or even 1000's of experiments. It's a clever approach: you have a real problem because the parameter space is so large but if you get 'close enough' to pick up an anomaly that might help you home in on something that is really promising. I'd love to see their notebooks and everything they tried. This is pretty much how we first got electric light: endless failures and then one success.
• mike_hearn 3y ago
  Well steady on there. The problem people have with bad science is not that there are misses, it's that there's no way for them to reliable decide when they've had a hit and so they end up inventing fraudulent pseudo-science. What's happening with LK-99 is science as people tend to imagine it working. Hypothesis -> experimentation -> replication -> theory. But that sort of science seems to be quite rare. Most science people are exposed in their daily lives is of the Francesca Gino variety, and that's not merely "a lot of noise with unknown variables", that's "nobody will care if we don't do real science so let's not bother".