4 ms·
> Using explants of human adipose tissue from individuals with obesity, in whom the adipose tissue accumulates senescent preadipocytes12, we confirmed that STIN
by everybodyknows 3y ago
> Using explants of human adipose tissue from individuals with obesity, in whom the adipose tissue accumulates senescent preadipocytes12, we confirmed that STING inhibition by H-151 suppressed the release of proinflammatory signals from senescent cells at the tissue level (Extended Data Fig. 3).