3 ms·
It’s discussed in the paper under the heading “ASD microbiomes mirror behavior improvement after fecal matter transplant” “To test this, we re-analyzed data fr
by Philadelphia 3y ago
It’s discussed in the paper under the heading “ASD microbiomes mirror behavior improvement after fecal matter transplant”
“To test this, we re-analyzed data from a 2-year, open-label fecal matter transplant (FMT) study with 18 children with ASD52. In this study, the children were subjected to a 2-week antibiotic treatment and a bowel cleanse, followed by 2 d of high-dose FMT treatment and 8 weeks of daily maintenance FMT doses. Based on one of the most common evaluation scales for ASD, the Childhood Autism Rating Scale (CARS), significant improvements were achieved after the 10-week course of treatment. Two months later, the initial gains were largely maintained, and a 2-year follow-up showed signs of further improvement in most of the patients. The results are consistent with a potential role of the microbiome in improving autism symptoms, but how the underlying changes in microbiome composition related to those seen in other studies remains unknown.”