Consider taxol resistance. Taxols prevent microtubule formation, but yet, somehow, cells find a way to overcome this. They have only tested this in mice. >> W

Consider taxol resistance. Taxols prevent microtubule formation, but yet, somehow, cells find a way to overcome this. They have only tested this in mice. >> We tested the anticancer activity of AOH1996 in mice bearing xenograft tumors derived from either neuroblastoma, breast cancer, or small cell lung cancer cells Cell function: https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(23)00221-0 https://www.cell.com/cell-chemical-biology/fulltext/S2451-94... Trials: https://www.cancer.gov/about-cancer/treatment/clinical-trials/search/v?id=NCI-2021-14102&r=1 https://www.cancer.gov/about-cancer/treatment/clinical-trial... I really hope this new chemo is powerful and adds to the list of agents we have to help stop metastatic cancer.