Years ago, yes I used it. Nowadays, to be honest, everything that I need to be fast in Python is largely around numerical code which either calls out to C/C++

Years ago, yes I used it. Nowadays, to be honest, everything that I need to be fast in Python is largely around numerical code which either calls out to C/C++ (via numpy or some ML library) or I use numba for. And these are either slower w/ PyPi or won't work. HTTP web servers are notoriously slow in Python (even the fastest ones like falcon) but I found they either didn't play nicely with Pypi or weren't any faster. In large part because if the API does any kind of "heavy lifting" they can't be truly concurrent.