All C extensions are available when running without GIL. A challenge for distribution is that all extensions will have to built twice to be compatible with the

All C extensions are available when running without GIL. A challenge for distribution is that all extensions will have to built twice to be compatible with the two Python builds. However, few source code changes are required where the developers don't want to make it compatible with running without GIL. Executing such extensions forces using the GIL for the whole interpreter, which is slower than the GIL-only build.