You provided an timeline of human evolution, but has fundamental physics changed at the core? Unfortunately, we haven't found any drop-in replacement to Newton

You provided an timeline of human evolution, but has fundamental physics changed at the core? Unfortunately, we haven't found any drop-in replacement to Newton's first & second laws for e.g.; Conversely, more & more of physics is condensing towards established standard models proving that our model of universe is more definite. In the quantum space our research is mostly finding new interactions, not fundamental particles everyday. Energy & it transformations are the biggest truths eventually. To propel crafts capable of interstellar voyage, immense energy burst is needed for propulsion. We have seen no evidence of the kind of physics which will break relativistic models - and no material which can sustain the thermals in the process. At the core of it, our chances to find another habitable world & intelligent species wherever they might be is rapidly reducing. Universe is expanding faster than previous estimated and probably double as old if you consider recent research. Our window of opportunity to establish contact passed probably before we came into existence. It is like predicting we'll be able to detect God by advances one day. That supernatural being could exist - but most scientific evidence points to a hard no, given we already know it is a mental / emotional construction.