4 ms·
Uh, that's a very simplistic headline that merits a big caveat: > This interaction is particularly dangerous when the drug in question has a low therapeutic in
by reefab 15y ago
Uh, that's a very simplistic headline that merits a big caveat:
> This interaction is particularly dangerous when the drug in question has a low therapeutic index, so that a small increase in blood concentration can be the difference between therapeutic success and toxicity.
Source: http://en.wikipedia.org/wiki/Grapefruit_juice_effect#Mechanism_of_the_interaction http://en.wikipedia.org/wiki/Grapefruit_juice_effect#Mechani...