If you mean memorable as in remember playing, definitely something from the NES era. Probably Dr Mario or Track and Field with the powerpad. If memorable in w

If you mean memorable as in remember playing, definitely something from the NES era. Probably Dr Mario or Track and Field with the powerpad. If memorable in which game itself left an impression, probably Skyrim. I think that was the first open world game I'd played, and it was at the time rather breathtaking.