The heart of the problem in life science is that "Experiments are always somewhere between too underpowered, too expensive and too unethical." Consequently, wh

The heart of the problem in life science is that "Experiments are always somewhere between too underpowered, too expensive and too unethical." Consequently, when you actually manage to run one to completion, everbody wants to squeeze every last itty bitty drop of possible juice from it. So, you will torture the data as far as you can for anything which even approaches significance. There's really no good way out of this. At the end of the day, the things you can do to humans are simply a lot more limited than the things you can do to inanimate objects.