I've had insulin responses before, but I believe there is an anticipatory response at play there. When I was on a relatively strict ketogenic diet in the past,

I've had insulin responses before, but I believe there is an anticipatory response at play there. When I was on a relatively strict ketogenic diet in the past, the recommendation was to test your blood sugar level after consuming a larger-than-average amount over the course of 1-2 hours to see if there were spikes or troughs from a hormonal response. Unless you have type 2 diabetes, any problem from a sugar-free insulin spike would likely be hunger. > If I had to guess we are going to get a big breakthrough study on diet pop that is going to link it to diabetes or something like that The Twin Cycle Hypothesis[0] predicts that many common cases of type 2 diabetes are from fat accumulation in the liver spilling to the pancreas and interfering with beta cell production of insulin. I wouldn't anticipate artificial sweeteners, even triggering an insulin response, to be able to do that without sugars also being consumed in tandem. > I remain skeptical that there is a free lunch here. Sugar-free gummy bears have quite the reputation because of how the gut reacts when you have a large quantity of sugar alcohols. It doesn't _have_ to be a cancer or a chronic illness. It can be more acute. [0]: https://pubmed.ncbi.nlm.nih.gov/23075228/ https://pubmed.ncbi.nlm.nih.gov/23075228/ (arbitrary first hit)