4 ms·
> But Campbell said when used via a spray, it would not be absorbed by the body This is a claim that appears to be presented entirely without evidence, and - a
by chimeracoder 3y ago
> But Campbell said when used via a spray, it would not be absorbed by the body
This is a claim that appears to be presented entirely without evidence, and - as written - is nonsensical. Nasal insufflation is an extremely common method for administering drugs, and it's readily absorbed directly into the bloodstream.
If there's a reason he believes heparin is not absorbed through this route, that's a notable and surprising claim.
- hirenj 3y agoAs far as I know, there’s no receptor for GAGs on cells to mediate their uptake specifically. Usually they hitchhike on some other protein that has a specific receptor/co-receptor. Heparin is actually a sulfated polysaccharide, and not like those other drugs that you might be thinking about.