Sure. Poor SMP support (but this has improved heavily over the years), ancient file system, no Bluetooth (not important if you don't need this), reduced perform

Sure. Poor SMP support (but this has improved heavily over the years), ancient file system, no Bluetooth (not important if you don't need this), reduced performance (due to a lack of optimizations and security mitigations overhead), limited Wi-Fi support (this is for numerous reasons, but it's better than other BSDs)... I could go on, but, for my needs, it works very well and some of its simplicities are a godsend.