The audio driver still matters, though. If you're on Windows rather than a Mac, not using ASIO will always incur a truly incredible latency, even with real MIDI

The audio driver still matters, though. If you're on Windows rather than a Mac, not using ASIO will always incur a truly incredible latency, even with real MIDI devices. Mac's Core Audio is quite a bit better in that respect, but pretty much everything ships with Asio4All for Windows users, and it's still an excellent idea to use it if you don't have an ASIO audio interface.