We've got a pretty good track record in predicting near-ish-future scientific/technological advances, which is what we would need for self replicating machines.

We've got a pretty good track record in predicting near-ish-future scientific/technological advances, which is what we would need for self replicating machines. To be clear, I'm not talking nanobots or similar - much more macro sized stuff. All the constituent pieces to make a self replicating mining robot or whatever are there today, and we already automate a lot of the processes required. There are some important gaps to fill, for sure, but none that we have any real reason to believe are insurmountable. We're in agreement that the 'why' is less clear, at least for probes exploring the galaxy. But there are some very clear reasons why this sort of tech in general is useful - mining the asteroid belt, building reflectors to better harness the energy of the sun, building all sorts of other infrastructure in space without having to use a rocket to get it there. At that point once we have the tech and are doing it - and I would be shocked if the human race is still around in 500 years and NOT doing that sort of thing - it's relatively cheap to kick off a bunch of probes doing similar things. I'm still not sure if it's worth it in that scenario, but it's conceivable that it could be. And that puts us again on the question of why we don't see it. We think there should be a lot of intelligent life out there. There's a lot of very important 'if's in all of this, but if we can think of it and and conceive of some potential reasons, and if other intelligent life has these capabilities that we believe will be possible, and if it becomes as resource/energy/time efficient to do as it should be, then it seems like someone, somewhere, should have been able to convince their government or corporation or whatever to do it, even if the results aren't necessarily going to be super apparent. The Pioneer plaque is obviously much cheaper, but we knew beforehand that the utility there is basically 0%. Like I said, I'm not necessarily arguing that these probes are out there. I'm guessing the answer is more likely "There's no compelling reason to colonize or even explore large swathes of the galaxy" and concerns around interstellar travel are on such large timescales that civilizations capable of interstellar travel would only care about their nearest neighbors. Maybe that changes as star formation spins down and the galaxy starts to slowly go dark and your local galactic resources are less and less abundant. I'm just saying that there are technosignatures that would indicate the presence of other intelligent life in the galaxy that have nothing to do with biological beings visiting us, and we would expect that some of these are possible for us to see now, if they're out there.