What is the role of stimulus during the growth phase of organoids? Meaning: is it sufficient to grow an organoid and then connect it to the electrodes and go t

What is the role of stimulus during the growth phase of organoids? Meaning: is it sufficient to grow an organoid and then connect it to the electrodes and go through the training process, or is there an advantage to growing the organoids _while_ connected to stimuli? Naively, it seems like our brains are growing while receiving input and that could guide the growth process.