One other consideration is how much of that is simply "mission accomplished". From my understanding, there's a sense SETI's raw dataset also just simply "shrun

One other consideration is how much of that is simply "mission accomplished". From my understanding, there's a sense SETI's raw dataset also just simply "shrunk" in the last several years. In the furthest distributed among general users period they were analyzing a lot of raw Arecibo data collected for other science needs and not already in the best shape for SETI experiments so a lot of it was "tedious grunt work". Between the shutdown of the Arecibo antenna and the stand up of dedicated SETI mission hardware (the Allen Telescope Array) built directly for their experiments a lot of the "tedious grunt work" just disappeared (and yes, as mentioned, doing more of the signal processing directly on site as the data is collected as part of the array design). Relatedly, from how I've heard it, protein folding hit a number of key milestones and solved a lot of (most of?) the most common/most generic proteins and their various folds. The biggest remaining problems are supposedly just ad hoc specialty projects for specific experiments/grant sponsors (in which case they can include computation resources in the experiment design/grant sponsorship) or specific rare events (the massive distribution asked for during the COVID-19 processing period). I think it is worth celebrating that apparently there was a good amount of "mission accomplished" science and that "use all the computation available for free from home users" period has mostly ended.