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This has been the story for decades now. Low blood levels of Vitamin D is highly correlated with just about every disease known to mankind. Yet, studies repea

This has been the story for decades now. Low blood levels of Vitamin D is highly correlated with just about every disease known to mankind. Yet, studies repeatedly have shown that Vitamin D supplementation has next to no benefit in curing those diseases. So either there's a jointly correlated third factor like sun exposure or low Vitamin D levels are CAUSED by those diseases and in general just an indicator of overall poor health.

deleted 3y ago
[deleted]
cpncrunch 3y ago
Sunlight does seem to correlate with reduced mortality, and there is speculation that the benefit is actually due to nitric oxide.
- tdstein 3y ago
  Interesting. Do you have any additional information on nitric oxide that you could link too?
  - Aerroon 3y ago
    I don't have a link, but nitric oxide in the body increases blood flow and reduces blood pressure. (Although I think it's only the upper number.)
    - solarmist 3y ago
      This has been known for a long time and is why bodybuilders use nitric oxide supplements before workout. Whether that does what they’re hoping is not proven, but it’s common and popular.
- phkahler 3y ago
  So take Viagra?
  - brodouevencode 3y ago
    L-arginine might be better
    - snapplebobapple 3y ago
      l-citrulline is better than L-arginine I believe. It's better absorbed, causes more nitric oxide production and doesn't cause the problems l-arginine does at higher doses (This is from my crappy memory but I am sure pubmed will be able to back this up. I am not in a space I can easily research sources again at the moment).
- jader201 3y ago
  > Sunlight does seem to correlate with reduced mortality Source? Every article/discussion that shows up here suggests the jury is still out in this as well.
  - Malic 3y ago
    TL;DW - The latitude you live at appears to have a correlation with general mortality. https://www.ted.com/talks/richard_weller_could_the_sun_be_good_for_your_heart https://www.ted.com/talks/richard_weller_could_the_sun_be_go...
  - slashdev 3y ago
    I've seen numerous findings that support this. It could just be cherry-picking, so do your own research. - High incidence of MS in northern hemisphere compared to low incidence near the equator. http://www.bandolier.org.uk/booth/neurol/MSgeog.html http://www.bandolier.org.uk/booth/neurol/MSgeog.html - Better outcome for skin cancer patients if diagnosed going into summer vs winter. https://onlinelibrary.wiley.com/doi/abs/10.1111/dth.13625 https://onlinelibrary.wiley.com/doi/abs/10.1111/dth.13625 There's a decent article on the subject on nih.gov here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290997/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290997/ And another by Harvard here: https://www.health.harvard.edu/diseases-and-conditions/benefits-of-moderate-sun-exposure https://www.health.harvard.edu/diseases-and-conditions/benef...
- antisthenes 3y ago
  It probably correlates with reduced mortality, because people exposed to sunlight tend to get out of the house more often and actually do some physical activity (that happens to be under the sun, sometimes).
  - cpncrunch 3y ago
    It would be a very poor study that didn't control for those factors! The reduction in mortality remains after controlling for level of exercise. Also, using sunbeds and sunbathing while on holiday is associated with reduced mortality, at least in this large study in Sweden: https://onlinelibrary.wiley.com/doi/full/10.1111/joim.12251 https://onlinelibrary.wiley.com/doi/full/10.1111/joim.12251
WillPostForFood 3y ago
Or that eating Vitamin D doesn't work the same way as Vitamin D naturally produced by the body.
Donckele 3y ago
Do you have a number for what a low level count is?
FollowingTheDao 3y ago
Or that population studies are not individual studies. Vitamin D 100% cures a vitamin D deficiency. And Vitamin D deficiency 100% causes disease. This study was only looking at how vitamin D supplementation affected a large swath of people, both those deficiency and those replete. So why is everyone surprised the results ar inconclusive?

deleted 3y ago

[deleted]

cpncrunch 3y ago

Sunlight does seem to correlate with reduced mortality, and there is speculation that the benefit is actually due to nitric oxide.

tdstein 3y ago
Interesting. Do you have any additional information on nitric oxide that you could link too?
- Aerroon 3y ago
  I don't have a link, but nitric oxide in the body increases blood flow and reduces blood pressure. (Although I think it's only the upper number.)
  - solarmist 3y ago
    This has been known for a long time and is why bodybuilders use nitric oxide supplements before workout. Whether that does what they’re hoping is not proven, but it’s common and popular.
phkahler 3y ago
So take Viagra?
- brodouevencode 3y ago
  L-arginine might be better
  - snapplebobapple 3y ago
    l-citrulline is better than L-arginine I believe. It's better absorbed, causes more nitric oxide production and doesn't cause the problems l-arginine does at higher doses (This is from my crappy memory but I am sure pubmed will be able to back this up. I am not in a space I can easily research sources again at the moment).
jader201 3y ago
> Sunlight does seem to correlate with reduced mortality Source? Every article/discussion that shows up here suggests the jury is still out in this as well.
- Malic 3y ago
  TL;DW - The latitude you live at appears to have a correlation with general mortality. https://www.ted.com/talks/richard_weller_could_the_sun_be_good_for_your_heart https://www.ted.com/talks/richard_weller_could_the_sun_be_go...
- slashdev 3y ago
  I've seen numerous findings that support this. It could just be cherry-picking, so do your own research. - High incidence of MS in northern hemisphere compared to low incidence near the equator. http://www.bandolier.org.uk/booth/neurol/MSgeog.html http://www.bandolier.org.uk/booth/neurol/MSgeog.html - Better outcome for skin cancer patients if diagnosed going into summer vs winter. https://onlinelibrary.wiley.com/doi/abs/10.1111/dth.13625 https://onlinelibrary.wiley.com/doi/abs/10.1111/dth.13625 There's a decent article on the subject on nih.gov here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290997/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290997/ And another by Harvard here: https://www.health.harvard.edu/diseases-and-conditions/benefits-of-moderate-sun-exposure https://www.health.harvard.edu/diseases-and-conditions/benef...
antisthenes 3y ago
It probably correlates with reduced mortality, because people exposed to sunlight tend to get out of the house more often and actually do some physical activity (that happens to be under the sun, sometimes).
- cpncrunch 3y ago
  It would be a very poor study that didn't control for those factors! The reduction in mortality remains after controlling for level of exercise. Also, using sunbeds and sunbathing while on holiday is associated with reduced mortality, at least in this large study in Sweden: https://onlinelibrary.wiley.com/doi/full/10.1111/joim.12251 https://onlinelibrary.wiley.com/doi/full/10.1111/joim.12251

WillPostForFood 3y ago

Or that eating Vitamin D doesn't work the same way as Vitamin D naturally produced by the body.

Donckele 3y ago

Do you have a number for what a low level count is?

FollowingTheDao 3y ago

Or that population studies are not individual studies. Vitamin D 100% cures a vitamin D deficiency. And Vitamin D deficiency 100% causes disease. This study was only looking at how vitamin D supplementation affected a large swath of people, both those deficiency and those replete. So why is everyone surprised the results ar inconclusive?