4 ms·
Is it possible to just edit the title to make it clear it's taking about stains? There is quite a bit of controversy about statins. I believe in double blind s
by psychphysic 3y ago
Is it possible to just edit the title to make it clear it's taking about stains?
There is quite a bit of controversy about statins. I believe in double blind studies it's not clear that more report muscle pain than placebo. (The rhabdomyolysis is clearly a possible side effect but distinct from just pain and weakness).[0] The absolute harm difference of 1% translates to a NNH of 100. One person is worse off due to being on a station vs placebo for every 100 prescribed. This NNH is much higher(better) that previously reported.
But are any better off? Ummmm, that's not too clear either it's proven on people with very very high cholesterol over 12 or so not your typical steak for breakfast eater who sits around 6.
Translated into extended quality of life it's probably not much.[1] Your looking at about 1.3% lower risk of death over 5 years mostly in the unhealthiest, exclude those with very high cholesterol and suddenly it doesn't seem so worth it esp if you factor in diabetes and being disincentivized to be healthy.
[0] https://www.bbc.co.uk/news/health-54951648 https://www.bbc.co.uk/news/health-54951648
[1] https://thennt.com/nnt/statins-for-heart-disease-prevention-with-known-heart-disease/ https://thennt.com/nnt/statins-for-heart-disease-prevention-...