I'm ADHD and I respond terribly to amphetamine (or Vyvanse). On low doses I become more irritable (or in my wife's words "an asshole"), and the one time I took

I'm ADHD and I respond terribly to amphetamine (or Vyvanse). On low doses I become more irritable (or in my wife's words "an asshole"), and the one time I took a higher dose (at the instruction of my psychiatrist because I wasn't getting a therapeutic effect at the lower dose), I had a manic episode and was awake for 36 hours straight. Finally settled on Focalin as working for me, but every time we changed insurance companies I had to spend a few hours on the phone proving to them that amphetamine doesn't work, while paying out-of-pocket until they are convinced.