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< https://en.wikipedia.org/wiki/Nicotine#Central_nervous_system https://en.wikipedia.org/wiki/Nicotine#Central_nervous_syste... > > Nicotine is unusual in comp
by joedeandev 3y ago
< https://en.wikipedia.org/wiki/Nicotine#Central_nervous_system https://en.wikipedia.org/wiki/Nicotine#Central_nervous_syste... >
> Nicotine is unusual in comparison to most drugs, as its profile changes from stimulant to sedative with increasing dosages, a phenomenon known as "Nesbitt's paradox" after the doctor who first described it in 1969.