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These new drugs are not a replacement for a health diet and exercise. Drugs like Ozempic, or Wegovy, aren't a permanent solutions, once you stop taking them the
by mrweasel 3y ago
These new drugs are not a replacement for a health diet and exercise. Drugs like Ozempic, or Wegovy, aren't a permanent solutions, once you stop taking them the effect stops and you can't take them forever. They are only meant to get you motivated and help start up a lower calorie diet.
We are also now seeing people where diet and exercise simply isn't working as expect. There was a study that indicated that PFAS pollution affects the metabolism in some people during the night. Normally you still burn calories while you sleep, but for some elevated PFAS levels causes their bodies to basically stop burning calories during the night.
You're not wrong the pushing lifestyle changes should be the primary goal, but the world isn't that black and white. Peoples circumstances are different and ignoring pharmaceuticals on principle isn't particularly productive. Just like ignoring lifestyle coaching is foolish.
- JediWing 3y agoThey're permanent as long as you keep taking them, like blood pressure medicines or statins.
- garciasn 3y agoIs it true that your body adjusts to the drug and once you stop taking it you can no longer process shit correctly, exacerbating the problems and forcing you to remain on it for life?
- hock_ads_ad_hoc 3y agoNo
- JediWing 3y agoI believe studies have mostly shown significant rebound upon cessation, but statistically it's been below 100% weight regain. Some anecdotes have people ceasing and getting heavier, but I don't think that's been shown at a population level.
- JimtheCoder 3y ago"There was a study that indicated that PFAS pollution affects the metabolism in some people during the night. Normally you still burn calories while you sleep, but for some elevated PFAS levels causes their bodies to basically stop burning calories during the night." I would be interested in reading that study...
- kenjackson 3y agoAnd for some (most) people they are fighting a huge uphill battle. An even slightly more efficient metabolism means if they eat the same as their peers who are in shape they will still gain weight. We need to recognize that caloric surplus and deficit is hugely impacted by deviations in many things that impact efficiencies (eg hormones, enzymes, etc…).