It sort of comes down to what you're comfortable with. In this case, the strict image analysis parts were more minor compared to the real work. Also, Matlab see

It sort of comes down to what you're comfortable with. In this case, the strict image analysis parts were more minor compared to the real work. Also, Matlab seems to be stagnating, while Mathematica has been growing by leaps and bounds. Also, matlab doesn't have built in functionality for gui building, afaik. A lot of my other work is much less suited to matlab. Mathematica is certainly much better for multi-domain work, which matlab barely supports.