I know a couple of folks doing the 'work from RV' thing (in very nice, recent vintage RVs), one couple who are on a good sized houseboat (on a very large lake),

I know a couple of folks doing the 'work from RV' thing (in very nice, recent vintage RVs), one couple who are on a good sized houseboat (on a very large lake), and a person or two who are on sailboats at least part time (fairly large...45'+). It seems to mostly work for them, tho even a big sailboat is pretty tight space wise (they're narrow). Given that, aside from the obvious challenges (Internet, etc.), my first thoughts are "a van is really, really small to live/work in for more than a couple of days at a time" and "depending on where you go, that van is going to either get really hot, or you're going to burn a lot of fuel to keep it cool". Perhaps rent a van for a week or two and live in it close to home to see if that works for you.