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What I always thought was interesting was that when you take psychedelics, despite whether it's mushrooms, LSD, or 2C-B (and what have you), you can feel this l
by gavinray 3y ago
What I always thought was interesting was that when you take psychedelics, despite whether it's mushrooms, LSD, or 2C-B (and what have you), you can feel this little ball of energy in your stomach (particularly noticeable when starting to come up) that persists for most of the trip.
My woo-woo theory is that there's some kind of serotonergic activity happening in the gut (which is responsible for some ~95% of the body's serotonin production) that is so profound you can physically feel it.
- Gibbon1 3y agoYour gut has it's own nervous system and sensory nerves including taste buds. I think the burden of proof would be on explaining why it's doesn't trip balls.
- wunderlust 3y agoHow do/would we know it doesn’t?
- pazimzadeh 3y agoThe main receptor for LSD is the 5-HT2A receptor. There is a ton of 5-HT2A receptors in the gut, mainly an enterochromaffin cells. The amount of 5-HT2A receptors expressed in the intestine increases as you go down the length of the intestine.