There's some research that shows that microdosing psilocybin isn't nearly (or at all) as effective as taking a regular dose. "Heroic" doses seem most promising

There's some research that shows that microdosing psilocybin isn't nearly (or at all) as effective as taking a regular dose. "Heroic" doses seem most promising from the neurological/neuroplasticity aspect, but yeah they can be... Quite something (even when you take care of S&S).