Regarding blisters, you absolutely can get blisters with toe socks, it just takes longer. I hike exclusively with Injiji Nuwool. On my JMT thru-hike I developed

Regarding blisters, you absolutely can get blisters with toe socks, it just takes longer. I hike exclusively with Injiji Nuwool. On my JMT thru-hike I developed large blisters on one toe on the side, and on another toe on the top. Also coincidentally areas where I wasn't wearing leukotape. In future hikes I made sure to leukotape top and sides and subsequently never had a blister again. I swear by pre-taping leukotape on long hikes to prevent blisters, more than the type of sock, but I do enjoy toe socks for the toe splaying thing since I wear Altra Lone Peaks (wide toe box shoes).